![]() ![]() “We see the cells like clay in our hands that we manipulate in culture and mimic development processes. We just accelerate the process that takes place in utero over nine months and follow the same stages in a shorter time period.” We have ways to maneuver stem cells to the destination and target tissue we want. Kadimastem’s lead product for ALS, AstroRx, is a cell therapy product containing astrocytes derived from human embryonic stem cells. The astrocyte cells are injected directly into the cerebrospinal cord fluid of the patients to support the dying motor neurons in the brain and spinal cord of ALS patients and slow progression of the disease. In March 2021, the company completed a Phase 1/2a clinical trial at Jerusalem’s Hadassah Medical Center, which validated safety and efficacy. The study results show a high safety profile of AstroRx cells and also demonstrated that this particular approach significantly decreased the progression of the disease for three months after AstroRx administration, when measured by ALS Functional Rating Scale-Revised (ALSFRS-S). The company aims to test multiple injections of AstroRx cells in the next round of clinical trials to try to prolong the beneficial effect.įor IsletRx, Kadimastem is working with global regulatory authorities to start pre-clinical studies this year. In April 2021, the company announced it had secured $6.8 million in financing to expedite its research and development programmes. “We anticipate that in about two years our diabetes product will be in clinical trials,” says Molakandov. ![]() In mice, we were able to show the dose escalating needed in order to achieve normal glycaemia, so we know most of the things that we need to know about these cells.” “In diabetes, we have managed to demonstrate that we have the capability to manufacture the islets in a good, reproducible way and our proof-of-concept studies show that our cells are capable of ameliorating glycaemia in diabetic animals. Kadimastem is also developing technology to purify non-relevant cells from the production procedure by selecting the right cells to put in the patient. In fact, Kadimastem is the only cell therapy company with this capability. Youth and adult archery leagues start up in January and March, so give us a call for details or to sign up.“It is not a process where you get everything you want – you sometimes get impurities, so we have a method and patent to take the right cells and put them in the patient. Associated with a local NASP Archery Program, stop in and check out the NASP equipment and discounts that we offer. We also have archery instructors for individual or group lessons if needed. You can also rent our range for birthday parties, scout troop meetings or corporate events. Never shot before? That’s OK because we can provide instruction with your rental for a little extra. We have different styles of bows to rent by the half hour or hour on our range. No need to worry about not having a bow or leaving yours at home. We have a 20-yard Indoor Archery Range to practice and hone your skills. Our expert technicians can assist you with the following archery services: Archery Services – Range Our archery technicians will help you with whatever you need to shoot like a pro. Our technicians will take the time to assist you with new equipment that you purchase or your existing equipment. Cabin Fever Sporting Goods – Archery DepartmentĪre you an archer in need of assistance with tuning or adjusting your bow? At Cabin Fever we have a full line of archery services to delight and intrigue everyone from the novice shooter to the seasoned hunter.
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